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Such upregulation of MMPs and VEGF is primarily responsible for remodeling of the ECM matrix

Glycyrrhizin Glycyrrhizin, a triterpenoid saponin extracted from the root of Glycyrrhiza glabra (licorice), has been reported to ameliorate psoriasis-like skin lesions by inhibiting TNF--induced inflammatory responses through the NF-B and MAPK signaling pathways, leading to decreased production of inflammatory cytokines (Xiong et al

10.1007/978-0-387-46401-5_6 78 LampeV.MiobdzkaJ

However, avoid using it with strong actives like retinoids or AHAs on the same dayyour skin doesn't need that much action all at once

doi: 10.1146/annurev.nutr.19.1.357, 4

The Tri-Peptide GHK-Cu Complex Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice