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Because drugs and biologicals on the FDA shortage lists are maintained at the NDC-10 level, and Part B drug inflation rebates are calculated at the HCPCS level, we proposed at 427.401(c) that if any NDC-10 assigned to the HCPCS code(s) is currently in shortage, we will apply the rebate reduction to all of the NDCs under the relevant HCPCS code(s)

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