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Besides, a series of UA derivatives with different amino acid and dipeptide substitutions at the C-3 position, MDA-MB-231, are synthesized, and some of these derivatives (e.g., 4c, 7a, 10a) shows high cytotoxicity against triple-negative breast cancer (MDA-MB-231) cells, and inhibits cancer cell proliferation and migration, induces apoptosis and autophagy through various pathways [1079]

This compound is further metabolized to hexahydrocurcumin and finally to octahydrocurcumin (hexahydrocurcuminol)

Journal of Complementary and Integrative Medicine (JCIM)

The liver relies on glutathione to eliminate toxins and harmful substances from the body

Biochem Biophys Res Commun 318(1):8894

Even before he hooked up with exploitation filmmaker and newly born-again zealot Ron Ormond, Pirkle was using props and skits to dramatize his sermons at Locust Grove Baptist Church in northern Mississippi