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Interestingly, bioinformatic analyses conducted on bulk tissue data obtained from healthy human brain tissue donors revealed that endothelial cells and microglia were the predominant senescent cell types, driven by CDKN1A/ p21 WAF1 /CIP1 (42) revealing potential differences in senescent cell types between healthy and diseased states

Cyanocobalamin's structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded

Intramuscular administration of their OspA mRNA candidate as a single dose induced innate responses similar to those elicited by an adjuvanted recombinant OspA protein vaccine

2017;313(5):H890H895