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Back in 2005, researchers conducted a randomized, double-blind, placebo-controlled study in 46 patients with ulcerative colitis

[DOI] [PMC free article] [PubMed] [Google Scholar] 181.Khalifeh S., Oryan S., Khodagholi F., Digaleh H., Shaerzadeh F., Maghsoudi N., Zarrindast M.R

While peptide-based therapeutics have been widely developed for class B GPCRs such as GLP-1R and PTH1R, the progress in small-molecule or orally administered drugs remains limited