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Instead, PPARa may primarily act through the FSP1 pathway to counteract ferroptosis

The geometric mean for the three most stable housekeeping genes were used to quantify changes in target gene mRNA expression in response to stimulation [29]

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DJ-1 protein acts as a neuroprotective factor by directly eliminating hydrogen peroxide, while cells expressing DJ-1 carrying PD-related mutations are sensitive to oxidative effects 10,154