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Furthermore, although injected fibrillar human -syn induced extensive -syn pathology and protein inclusions in A53T transgenic mice, in E46K transgenic mice -syn pathology was predominantly localized to the site of injection with no evidence for spread (Sacino et al., 2014)

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J.VidalM.RagagninA

Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences

Those that are not absorbed move down to the large intestine where they may be metabolised by the microbiota (Figure 1b)

Recent findings suggest that this macrophage transition is, at least partially, mediated through lactylation, a post-translational modification where lactate groups are added to lysine residues of proteins [134]