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doi: 10.1242/jcs.03239 13 BovenschenNKummerJA

Several ROS generated by unstable types of oxygen, including the superoxide ion, hydrogen peroxide, and hydroxyl radicals, are the principal pro-oxidant molecules ( The intestinal epithelium has been acknowledged as a crucial factor in the development of IBD due to its dual nature of exhibiting both immune and organ-specific functions

Mitochondria are both a source and a target of ROS [85]

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