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Once you hit it, the receptors in your body are saturated

In addition, RRM2 may exert its regulatory role by activating EGFR/AKT

This project has been supported by grants from the Swiss National Science Foundation [CR20I3-146431, 31003A-176206 and 197942 to C.S

Nature 483 , 222226 (2012)

These steps are catalyzed by dihydrouracil dehydrogenase (dihydropyrimidine dehydrogenase), dihydropyrimidinase (dihydropyrimidine amidohydrolase), and 3-ureidopropionase (-alanine synthase), respectively [11,20,26,27]