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Journal of Endocrinological Investigation, 47(3), 567-578

Because tumor growth also depends on new blood vessels, several reviews describe this as a theoretical concern that has not been resolved in humans (Sehgal et al., Pharmaceuticals, 2025)

During the proliferation phase, neovascularization is essential for delivering nutrients and oxygen to the wound site, thereby promoting fibroblast proliferation, collagen synthesis, and re-epithelialization 73

This treatment may be considered by patients dealing with joint discomfort, soft tissue concerns, or those interested in optimizing recovery after physical strain

Clinical wound healing studies involving direct application to open wounds have shown good tolerability without significant adverse effects, and wound healing outcomes are generally improved rather than impaired

The Johns Hopkins University