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The IL-20 subfamily of cytokines--from host defence to tissue homeostasis

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The safety, tolerability, pharmacokinetics and pharmacodynamics of an optimized dual GLP-1/GIP receptor agonist (BGM0504) in healthy volunteers: a dose-escalation phase I study

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A significant gap persists regarding the mechanistic role of GADD45 in hepatic lipid metabolism, particularly its interactions with established pathways such as SIRT1/AMPK/sterol regulatory element-binding protein 1 (SREBP1) signaling, which are crucial for maintaining metabolic homeostasis 10,11