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This means that thyroid cells need to maintain their level of oxidative stress within a certain range, rather than uniformly attempting to lower it by producing more anti-ROS enzymes and molecules like glutathione

10.1084/jem.20182386 [DOI] [PMC free article] [PubMed] [Google Scholar] Doll J

Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism

Endometriosis and assisted reproductive technologies: are outcomes affected

showed that intracellular glutamate accumulation following cyst(e)ine depletion or system x C - inhibition is a key contributor to the induction of ferroptosis, and glutamate toxicity can be alleviated by converting excess glutamate to -glutamyl-di- or tripeptides via promiscuous enzymatic activities of glutamate-cysteine ligase catalytic subunit (GCLC) 12

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