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10.1016/j.jcf.2021.01.010 J Cyst Fibros

One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)

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CAR may also indirectly suppress the APR by inhibiting IL6 production

GST Tag Cross-Reactivity Challenge : The GST tag can sometimes exhibit cross-reactivity with other proteins or reagents, leading to non-specific binding in assays and purification steps