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Through insulin resistance (IR) and high levels of insulin and androgens, the adipose tissue is responsible for ovulatory disorders in disposed patients and the anovulation associated to obesity is responsible for higher risk of miscarriages and infertility ( In patients without ovulatory disorders, overweight and obesity extend the time to conceive, decrease the outcome of infertility treatment and increase the rates of gestational diabetes, hypertension, cesarean section, overweight newborns, perinatal mortality and morbidity

Statements Author contributions JZ: Writing review & editing, Writing original draft

doi: 10.1111/andr.12172

The Gut Microbiome Affects Phase I and Phase II Enzymes The gut microbiota can also indirectly affect expression of detoxification enzymes

It is your bodys primary antioxidant defense system

Microarray studies on the genes responsive to the addition of spermidine or spermine to a Saccharomyces cerevisiae spermidine synthase mutant