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Discussion: These findings suggest that biased GPR3 signaling modulates microglial activity and the response to A accumulation, providing a potential therapeutic target in AD

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Training Specificity: Calculation of the Whole Frequency Spectrum Finally, training specificity can be determined by repeating steps in Section Measures Assessing Changes of Brain Activity during Neurofeedback for different frequencies, assessing whether the target feature or frequency of interest has been predominantly modulated