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Inhibiting pathways associated with ammonia-induced cell death can enhance CD8+ T-cell survival, significantly improving the effectiveness of adoptive cell therapy ( Current targeting strategies continue to confront a triple paradox: First, while inhibition of glutamine metabolism enhances memory differentiation of T cells (60), it may exacerbate nutrient competition within the tumor microenvironment

(2002) High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms

Experimental data suggests that flavonoids, structurally resembling benzodiazepines, show antiepileptic properties through the modulation of the GABAA-Cl channel complex

GH-releasing hormone induces cardioprotection in isolated male rat heart via activation of RISK and SAFE pathways

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Occasionally a mouth ulcer can become secondarily infected with bacteria