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Although immunohistochemical analyses have found B cell-rich tertiary lymphoid structures in most brains from patients with MS, but not in the two PD patients investigated (92), there is ample evidence for the involvement of B cells, antibodies, and humoral immune effector mechanisms in PD (9395)

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doi: 10.1016/j.arr.2024.102204 [DOI] [PubMed] [Google Scholar] 138.Martini H, Passos JF

doi: 10.1016/J.ACA.2019.02.036 180 PerrinL.SpinosiJ.ChaperonL.KabS.MoisanF.EbazA

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Likewise, a 6-month treatment with NAC in EP patients reduced plasma soluble RAGE, increased prefrontal GABA levels, and enhanced cognitive function [58]