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Along with (-)-epicatechin-3-sulfate (E3S) and 3-O-methyl-(-)-epicatechin-5/7-sulfate, these three metabolites accounted for the major SREMs detected in human circulation (Ottaviani et al., 2012)

Mitochondria Mitochondria are double-membrane organelles responsible for generating most cellular ATP through oxidative phosphorylation 83

doi: 10.1212/01.wnl.0000261919.22630.ea 190 SaeedU.MirzaS

Hydroxyl radical is one of the most reactive radicals with a short lifetime, about 10 8 10 9 s

In parallel, we address the emerging field of chrononutrition, emphasizing that the timing of food intake and consumption of melatonin-rich or polyphenol-containing foods can enhance circadian rhythmicity, improve sleep quality, and reduce age-related metabolic and oxidative stress

It is particularly worth mentioning that the H 2 S response range of DCNP@PB is highly matched with the H 2 S concentration at the tumor site, which provides a strong guarantee for the specific detection of colorectal tumors in a complex physiological environment (Table 1)