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After 24-h induction with fatty acids, the intracellular lipid accumulation increased and the expression of -smooth muscle actin increased, indicating that the hepatic stellate cells were activated and the cells showed the characteristics of steatosis and fibrosis

Ng and colleagues (2000) demonstrated that the fragment stimulated lipolysis in isolated rat adipocytes with potency comparable to full-length hGH, while failing to elicit growth-promoting or glucose-disrupting effects

These results indicate that clotrimazole, a widely used drug for the management of a variety of superficial dermatophyte infections of the skin, is a potent inhibitor of cytochrome p450 dependent transformation of polycyclic aromatic hydrocarbons in cultured murine keratinocytes

Transient depletion of lung glutathione by diethylmaleate enhances oxygen toxicity