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10.1016/j.neuroim.2008.12.002 J

Patient selection should align with mechanism of action and health status

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Reduced Glutathione Recycling: The body has a natural system for regenerating used glutathione, but NSAIDs may impair this process

In animal models, lithium increased intracellular glutathione levels and reduced oxygen metabolite damage, suggesting that it selectively boosts glutathione-dependent enzymes to protect against free radical stress