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Constituents, pharmacokinetics, and pharmacology of Gegen-Qinlian decoction

Evidence of abnormal mitochondrial ultrastructure in hepatocytes of patients with Wilsons disease supports the theory that mitochondria are one of the affected organelles in copper toxicity.17 There is also evidence to suggest that the mechanism of hepatocyte death in Wilsons disease is via apoptosis that may explain the typical mild elevation in the transaminases associated with hepatitis in Wilsons disease.18 Clinical Presentation One of the challenges of diagnosing Wilsons disease is the wide spectrum of clinical presentations

ALCAR has shown to improve blood flow to the brain, thus potentially improving memory, and overall cognitive function while significantly improving metabolic function, while simultaneously lowering oxidative stress and free radical production

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Amiodarone is another consideration but care should be exercised and patients monitored closely for side effects 19