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The theory here is that if you're targeting a specific, deep muscle injury (like a quad tear or a deltoid strain), injecting directly into that muscle might provide more localized benefits in addition to the systemic effects

Van Ganse E, Danchin N, Mah I, et al

Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial

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NetMHCpan-4.0: improved peptideMHC class I interaction predictions integrating eluted ligand and peptide binding affinity data