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Best Pract Res Clin Endocrinol Metab (2003) 17(3):36583

As summarized in several reviews 7,8,9,10,11 , GRXs are characterized by a thioredoxin fold which consists of a central four-stranded -sheet surrounded by three -helices

However, many plant-based derivatives are also available, which can be helpful

The peptides don't compete or interfere with each other

doi: 10.1016/j.bbrc.2024.150683 50 SongM.KimW

We applied a 3-pronged approach to obtain a comprehensive assessment of diabetes-induced effects in xenograft breast tumors, patient tumors, and human breast cancer cell lines, as outlined in Supplemental Figure 1C