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Cardiovascular effects: Glucagon receptor agonism (via retatrutide) and GLP-1 receptor agonism have been associated with modest increases in heart rate as a class effect

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That said, safety is generally a function of health and dosage, so it is important that you speak with a registered healthcare provider before beginning the therapy to rule out any contraindications and get ongoing evaluation of your progress

Some individuals may benefit from combining both approaches under medical supervision

Handling and use are restricted to qualified or licensed professionals only, at least 21 years of age

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