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Description

PMID: 27013460

2019;316:H1366h1377

The reaction mixture was retrotranscribed at 48 C for 45, denatured for 2 at 94 C and then subjected to 1826 cycles of denaturation for 30 seconds, annealing at 55 C for 45 seconds, and elongation at 68C for 1 minute

Importantly, Berg et al

The activated Nrf2-sMaf heterodimer binds to antioxidant response element (ARE) sequences in the promoter of a tandem of antioxidant genes, including heme oxygenase-1 (HMOX1), aldo-keto reductases, glutathione, and glutathione-S-transferase (Tonelli et al., 2018), to trigger their expression