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J Clin Pharmacol 37(2):92100 Zalcberg J, Kerr D, Seymour L, Palmer M (1998) Haematological and non-haematological toxicity after 5-fluorouracil and leucovorin in patients with advanced colorectal cancer is significantly associated with gender, increasing age and cycle number

With the introduction of new mechanisms like HO and ROS, research gradually shifted toward theranostics integration, as well as multimodal synergistic treatment, driving innovative applications of nanomaterials in disease imaging, targeted therapy, and functional integration