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AOD-9604 is a synthetic 16-amino-acid peptide based on the tail end of human growth hormone, with an extra tyrosine added to one end

10.1021/acs.jmedchem.2c01166 13 BelenkyP.BoganK

It is considered investigational, which is precisely why medical supervision is essential before considering it

It is a comparatively recent discovery and a fast-growing subject of metabolic and longevity research

Numerous studies have documented a reduction in NAD + levels across various mouse tissues, including adipose (Yoshino et al., 2011), skeletal muscle (Frederick et al., 2015), liver (Trammell et al., 2016), and hypothalamus (Sasaki et al., 2014), concomitant with the development of obesity

At the highest dose, lesions ranged from minimal to moderate