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Three-and 7-month-old Tg4-42 and mice showed significantly decreased 18 F-FDG uptake in the hippocampus compared to WT mice (Fig

It may provide the link between inflammation and insulin sensitivity

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its deficiency can induce cell cycle arrest, senescence, apoptosis, and reverse drug resistance, and is positively correlated with Sox2 expression in clinical tissues, providing a new direction for targeted therapy [142]