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Zhang Y, Yuan M, Bradley KM et al (2012) Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function

A single course of phenobarbital for alcohol withdrawal (10-20 mg/kg cumulative dose within a short period of time) is unlikely to cause substantial enzyme induction

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Conversely, the de novo pathway and Preiss Handler pathway synthesize NAD + using nicotinic acid (NA) and tryptophan as substrates, respectively, albeit in smaller quantities