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For this purpose, we examined an evaluation cohort of 29 well-phenotyped homocystinuria patients (for genotypes and phenotypic characteristics see Additional file 2: Table S6)

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Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation

CHAC1 is a downstream effector of several key signaling pathways, including the RhoA-ROCK1 and p38 MAPK pathways, which are modulated by tumor suppressors like ARHGAP6

6.3.1 ABTS (2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)) methodology The ABTS protocol evaluates antioxidant efficacy through the neutralization of pre-generated ABTS + radical cations (Deadman, 1973)

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