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HPLC/mass spectrometry quantification of 8-oxo-dG DNA was extracted from brain tissues using standard phenol chloroform methodology for which the methodological details have been published previously

Finally, we considered some potential molecular target expressed by the TME which can help to relieve the TME-mediated immunosuppression

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However, recent advances in understanding the pathogenesis of Graves orbitopathy have allowed the development of new target-based therapies by blocking pro-inflammatory cytokine receptors, lymphocytic infiltration or the insulin-like growth factor 1 receptor (IGF1R), with several clinical trials providing promising results

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