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Mechanistically, neuronal death protection from autophagy seems to involve the MET downstream mTOR signaling, whose activation (phosphorylation) is enhanced after tMCAO (Shang et al., 2010)

22 Citicoline neuroprotection may involve multiple pathways, including the attenuation of phospholipase A 2 activation, stimulation of phospholipid synthesis, and increases in glutathione

PPIs block the H+/K+ ATPase pump within parietal cells, consequently diminishing the transportation of H+ ions into the gastric lumen

[DOI] [PubMed] [Google Scholar] 79.Ji L, Deng H, Xue H, Wang J, Hong K, Gao Y, Kang X, Fan G, Huang W, Zhan J, You Y

-Glutamyltransferase enzyme activity of cancer cells modulates L--glutamyl-p-nitroanilide (GPNA) cytotoxicity