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Elevated intracellular GSH levels cleave disulfide bonds, triggering degradation or structural rearrangements in nanocarriers

May potentially get with the help of exactly the same factors

Int J Mol Sci 21 Trammell SA, Brenner C (2013) Targeted, LCMS-based metabolomics for quantitative measurement of NAD(+) metabolites

These results indicate that (a) treatment with a high initial concentration (40 M) of NFT led to sustained elevation of intracellular glutathione levels for up to 48 h