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This explains why some people need surprisingly high doses despite normal absorption

10.3389/fnagi.2020.511562 Front

The release of 3-hydroxybutyrate from AdV-CMV-Cre-GFP transduced astrocytes was significantly reduced, suggesting impaired ketogenesis in CPT1A KO astrocytes (Supplementary Fig

EEG, electroencephalography

PTP1B was upregulated by APAP in primary human and mouse hepatocytes together with the activation of c-jun (NH2) terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK), resulting in cell death

Curr Top Med Chem 13:32053224 Biri-Kovcs B, Bnczi Z, Tummalapally A, Szab I (2023) Peptide vaccines in melanoma: chemical approaches towards improved immunotherapeutic efficacy