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Owing to the pronounced heterogeneity of IBD, biologics and small-molecule agents elicit highly variable responses, with approximately 3040% of patients experiencing primary or secondary loss of response [17]

Henson J, Capuano S, Nesbitt D, Hager D, Nundy S, Miller D, Ballatori N, Boyer J

Each measurement was subsequently corrected for the expansion factor

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"But if you're thinkin' about my baby it don't matter if you're black or white," MJ sings

The diffraction data were indexed and integrated using the XDS program [30] and then scaled using XSCALE [30]