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T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays

The establishment of standardized protocols for biomarker assessment in clinical settings remains an ongoing challenge

The expanding world of oxidative protein folding

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Tesofensine carries CNS-related side effects consistent with monoamine reuptake inhibition: insomnia (reported in 18% of participants), dry mouth (32%), constipation (17%), and dose-dependent increases in heart rate and blood pressure

Further investigations have identified two broad categories of organ failure in AP: early primary organ failure, which occurs within 72 h due to systemic inflammation, and late secondary organ failure, which typically develops after one week and is often linked to infectious pancreatic necrosis