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Beyond their established effects on DNA methylation, SeNPs have been shown to modulate histone methylation by influencing the expression of specific histone methyltransferases (HMTs) such as EZH2, SETD7, and SUV39H2/KMT1B, and by altering the S-adenosylmethionine (SAM)/S-adenosylhomocysteine (SAH) ratio through the transsulfuration pathway

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doi: 10.1021/acs.nanolett.3c03580 181 YiuT

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It is estimated that the average time for fibrosis progression per stage in patients with MASLD is approximately 14 years, while in those with MASH, this period is roughly halved to about 7 years

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Tilley, Barbara C|Mainous, Arch G|Smith, Daniel W|McKee, M Diane|Amorrortu, Rossybelle P|Alvidrez, Jennifer|Diaz, Vanessa|Ford, Marvella E|Fernandez, Maria E|Hauser, Robert A|Singer, Carlos|Landa, Veronica|Trevino, Aron|DeSantis, Stacia M|Zhang, Yefei|Daniels, Elvan|Tabor, Derrick|Vernon, Sally W Design of a cluster-randomized minority recruitment trial: RECRUIT Clinical Trials [17407745]

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