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The activity of blood SOD was increased significantly to reach normal or about normal values following the administration of H.pylori eradication therapy or nizatidine in combination with either vitamin E, thioctic acid or a combination of both agents.The normalization and /or significant elevation of blood SOD activity in H.pylori -infected duodenal ulcer patients may be attributed to the capacity of antioxidant vitamins to scavenge H.pylori -generated H 2 O2 and superoxide anion radicals thus saving SOD activity [75]

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Silicosis is characterized by irreversible lung fibrosis [1] and is one of the most widespread occupational diseases in the world, especially in low- and middle-income countries [2]

Considering that metformin-induced mitochondrial complex I inhibition impairs NADH oxidation and elevates NADH levels, these transcriptional changes probably represent a compensatory adaptation to restore redox homeostasis by enhancing NADPH generation

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Neuroimmune mechanisms underlying neuropathic pain: the potential role of TNF--necroptosis pathway