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Nursing animals and young, rapidly growing animals develop iron deficiency more easily than adults on an iron-replete diet, particularly if there is a concurrent source of external blood loss: iron stores in young animals tend to be marginal, milk is low in iron, and rapid growth demands expansion of blood volume

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Tryptophan increased also the circulating levels of melatonin, particularly in the portal circulation and these changes of melatonin levels in GIT following tryptophan application were unaffected by prior pinealectomy, but greatly reduced by a partial ligature of the portal vein (8)

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