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Therefore, reduced levels of -ketoglutarate might lead to the inactivation of PHD-2 and FIH-1, thereby facilitating the stabilization and transcriptional activity of HIF-1 (Koivunen et al., 2004)

(1981a) Mutagenicity study of workers exposed to alkene oxides (ethylene oxide/propylene oxide) and derivatives

Guan C, Cui X, Liu HY, Li X, Li MQ, Zhang YW

These transcription factors play a critical role in regulating various cellular processes, including apoptosis (programmed cell death), oxidative stress response, and cell cycle regulation

5 Clinical application prospects The gut microbiome and its metabolites have emerged as actionable modulators of the gut-tumor-immune axis, offering a framework to enhance cancer immunotherapy efficacy through targeted microbial manipulation

How testosterone is produced The process of making testosterone starts with cholesterol