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Brain anatomy and development in autism: review of structural MRI studies

106 Thioredoxin Thioredoxin is a 12 kDa ubiquitous oxidoreductase that is central to the thioredoxin antioxidant system consisting of thioredoxin, NADPH and thioredoxin reductase

An autoimmune disorder where the immune system stays active all the time

Cognitive improvements were evident at doses of 200, 400, and 800 mg/kg/day, as confirmed by passive avoidance and Y-maze tests (Lim et al., 2018)

Since fundamental biochemical pathways evolved in the absence of molecular oxygen, most intracellular disulfides are rather transient and most cysteinyl residues are kept in a reduced state with the help of the thioredoxin or the glutathione/glutaredoxin system 7,63,77

The current study will examine the empirical evidence supporting the metabolic targets of these treatments