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Introduction Glutathione (GSH) is a tripeptide containing a -amide bond and a sulfhydryl group composed of glutamic acid, cysteine (CYS), and glycine and is present in almost every part of the body cell ( Weaning transition is considered a very stressful period in pigs' life because piglets must adapt to the new living environment, should mingle with pigs from different litters, and consume completely different diets ( Therefore, the experiment of dietary GSH addition to the weaned piglets was designed to investigate the kinetics of GSH in the gastrointestinal tract and the distribution of GSH in intestinal and hepatic tissues and in blood erythrocytes

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