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Because of the slow onset of action and the potential for side effects, however, 6-MP and azathioprine are used mainly in the following situations: Patients with ulcerative colitis and Crohn's disease do not respond to corticosteroids

Collectively, these data suggest that signalling through DAF12 is required to maintain protein homeostasis

Zhang Y, Yu C, Li X

Moreover, excessive cholesterol often contributes to an immunosuppressive environment in CRC, promoting immune evasion

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For example, the deletion of JA in the tomato was previously shown to reduce photosynthesis, weaken the defense ability of the antioxidant system, and enhanced sensitivity to Cd [32]