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When cells face oxidative stress, including metal-induced stress, KEAP1-mediated degradation of NFE2L2 is inhibited, leading to its stabilization and nuclear translocation

60 In conclusion, TSS inhibits the progress of endometriosis due to anti-inflammatory and anti-angiogenic pharmacological activities

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Tightening the barrier could reduce the negative effects of the inflammation challenge or in the presence of any of the neurodegenerative diseases, controlling the integrity of the BBB could slow the progression of the disease and neurodegeneration