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Alamanos Y, Drosos A

Cells that overexpress BMAL1 showed increased, NQO1, SOD, Nrf2, Prdx6s mRNA, and protein levels, and this increased expression is closely linked to decreased ROS levels

As ATP production becomes more efficient and less toxic, patients often report a gradual lifting of the heavy, leaden feeling in their limbs, a reduction in the severity of post-exertional crashes, and an improvement in their overall stamina and cognitive clarity

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2023a, b)

The massive quantities of present oxygen enabled the production of more ATP via aerobic respiration but also increased the danger of ROS formation