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Interestingly, a specific GPX1 polymorphism resulting in a proline-to-leucine transition at position 198 (Pro198Leu) is associated with a reduction in GPx1 activity and found to be more prevalent in Keshan patients

Its selectivity makes it particularly relevant in experimental models focused on controlled receptor activation and signal precision

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PMID: 37694677

van den KerkhofMde JongJVoorterPPostmaAKroonAvan OostenbruggeRet alBlood-brain barrier integrity decreases with higher blood pressure: a 7T DCE-MRI study

In the hippocampus, mRNA expression was elevated for GRIA1 in the rmTBI group but not the ALC + rmTBI treatment group