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Given the shared microbiota changes in GD and depression (26, 150154), as well as the potential effects of microbiota dysbiosis in GD on depression, probiotics and symbiotics may exert beneficial effects in improving the intestinal flora environment of patients with GD, thus reducing the risk of depression

Biochemistry 37:1557515582 Holmgren A (1985) Thioredoxin

Based on the nucleotide sequences of the target genes, development of primer sets were designed and used to amplify gene fragments by PCR (Additional file 1: Tables S1S6)