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Its essential for: Red blood cell formation Neurological function DNA synthesis Metabolism of fats and carbohydrates Energy production Since B12 is naturally found in animal products such as meat, dairy, and eggs, individuals following vegetarian or vegan diets are often more susceptible to deficiencies

Jean Kwun, [email protected] These authors have contributed equally to this work This article was submitted to Alloimmunity and Transplantation, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Pyrrolidine dithiocarbamate up-regulates the expression of the genes encoding the catalytic and regulatory subunits of gamma-glutamylcysteine synthetase and increases intracellular glutathione levels

Each time the body detoxifies a compound, metabolizes alcohol, or counters oxidative stress from exercise or pollution, glutathione is used up

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