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Www.vanderbilt.edu

Turek et al., 2005

Circ Res 2018;122:62438

Takeshima, Y., Iwasaki, Y., Fujio, K

2-[[[(2-Methoxy-6-methylphenyl)amino]carbonyl]amino]-N-(2,4,6-trimethylphenyl)-6-benzothiazolcarboxamid

Charges, coulombic and H-bonding interactions with neighboring functional groups In general, neighboring functional groups that stabilize the charge distribution of the transition state accelerate, and interactions that lower the energetics of the reactant complexes inhibit Reaction 1