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Thyroid autoimmunity: role of anti-thyroid antibodies in thyroid and extra-thyroidal diseases

In a study, it was discovered that the upregulation of ornithine decarboxylase 1 (ODC1) and arginase 2 (ARG2), which are key enzymes in the urea cycle, led to enhanced ornithine catabolism and activation of the intracellular mTOR/ROCK1 signaling pathway in podocytes

Shown is the uptake of GSH-targeted liposomes by Bovine capillary endothelial cells (BCECs) in BCECs monoculture (A) and in the BBB co-culture model (B)